Pharmaceutical delivery technology

A Small Sphere.
A World of Possibilities.

Discover how a distinctive hollow, porous architecture is opening new possibilities in pharmaceutical formulation and drug delivery.

Light-blue-tinted ARC Hitachi SEM of the porous wall of a hollow glass microsphere, cropped for the homepage hero

The SpheroFill platform

Engineered architecture.
Expanding possibilities.

SpheroFill's porous-wall hollow glass microspheres combine a distinctive internal structure with surfaces that can be engineered for research into pharmaceutical applications.

Explore the architecture that makes this platform an intriguing subject for formulation and delivery research.

Explore the Five Technology Pillars
Cutaway visualization supplied by SpheroFill showing a smooth microsphere exterior, porous wall, and hollow internal cavity.

Porous architecture

Interconnected wall pores offer pathways for molecular transport.

Hollow interior

An internal cavity offers space to investigate compound loading.

Engineerable surface

Surface chemistry creates opportunities to study material interactions.

Versatile platform

A single architecture invites exploration across multiple formulation concepts.

Manufacturing development

Process consistency and scale-up are important areas for continuing work.

Potential applications

Exploring what this platform could make possible.

From formulation challenges to site-specific delivery concepts, SpheroFill is investigating where this distinctive architecture may open new possibilities across pharmaceutical development.

Formulation possibilities

Investigating approaches to solubility, stability, and pharmaceutical formulation.

Localized delivery concepts

Exploring the potential for site-specific therapeutic delivery.

Release opportunities

Investigating approaches to sustained and tunable delivery.

Scientific foundations

Built on research.
Expanding through continued investigation.

Our work draws on published research, patented innovations, and ongoing scientific investigation. Explore the scientific foundation of the platform through our published research and patents.

Research

Scientific investigations of porous-wall hollow glass microsphere structure and potential applications.

Patents

Intellectual property addressing microsphere technologies and applications.

Development

Continuing research to refine understanding and evaluate emerging possibilities.

SpheroFill Insights · Podcast

Tiny Bubbles, Big Possibilities.

Discover the origins of porous-wall hollow glass microspheres, what makes their architecture distinctive, and the scientific questions inspiring new approaches to drug delivery.

Episode 1 · Introducing Porous-Wall Hollow Glass Microspheres

SpheroFill Insights podcast artwork: hollow microsphere with magnified porous wall

About SpheroFill

Meet the leadership team.

Bringing together experience in clinical medicine, materials science, and regenerative medicine, SpheroFill was founded to explore the biomedical possibilities of porous-wall hollow glass microspheres.

Co-founder

Paul M. Weinberger, MD

Interim CEO

Physician-scientist, fellowship-trained laryngologist, and healthcare executive. Dr. Weinberger combines clinical research and health-system leadership with experience translating biomedical technologies and developing SpheroFill's intellectual property.

Co-founder

George Wicks, PhD

VP Research & CTO

Materials scientist and former Savannah River National Laboratory senior researcher. Dr. Wicks brings decades of experience in glass and ceramic science, including the origins and engineering of porous-wall hollow glass microspheres.

Co-founder

William (Dave) Hill, PhD

Executive VP & CSO

Biomedical scientist with extensive experience in regenerative medicine, stem-cell biology, and translational research. Dr. Hill connects SpheroFill's materials platform with opportunities for biological investigation and pharmaceutical development.

Leadership expansion

Coming Soon

Pharmaceutical Business Leadership

We are in the process of adding seasoned pharmaceutical business leadership to support partnerships, strategy, and commercialization.

Let's explore what's next

A platform for collaboration.
A path to impact.

We welcome conversations with pharmaceutical partners, scientific collaborators, and investors who share our interest in advancing this technology.

For pharmaceutical partners

Explore development opportunities, collaborative research, and potential partnerships.

Start a conversation

Connect with SpheroFill

Let's start a conversation.

Interested in the science, exploring a partnership, or learning about SpheroFill? We'd welcome the opportunity to connect.